The development will serve as the basis for the creation of specific therapies and prevention of COVID-19.
NOVOSIBIRSK, July 15. / TASS /. Employees of the immunogenetics laboratory of the Institute of Molecular and Cellular Biology (ICMB) SB RAS, located in Novosibirsk, for the first time in Russia received antibodies that neutralize coronavirus. Further development of this work will serve as the basis for the creation of specific therapy and prevention methods for COVID-19, Olga Dorokhova, executive secretary of the SB RAS working group on overcoming a new coronavirus infection, told TASS on Thursday.
“At the Novosibirsk Scientific Center, the first in Russia to receive active antibodies to COVID-19. For this, we used blood samples from ill COVID-19 donors and a unique technology for sorting single B-lymphocytes (blood cells responsible for the formation of immunity – approx. TASS). The resulting antibodies are able to block the interaction of the virus and the ACE2 cell receptor (a protein embedded in the cell membrane) and, accordingly, prevent its penetration into target cells, ”the agency’s interlocutor said.
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According to Dorokhova, further development of the study will allow scientists to create means of specific therapy and prevention of COVID-19. In addition, the results obtained will serve as material for studying the features of protective immunity in coronavirus infection and will be in demand in the development of vaccines.
The immunogenetics laboratory of the ICMB SB RAS is engaged in the creation of molecular diagnostics and therapy of human diseases. Institute of Molecular and Cellular Biology SB RAS, one of the youngest institutes of the Novosibirsk Academgorodok, created in 2011. He conducts research in the following scientific fields: immunogenetics, cell technology in medicine. In addition, employees of the institute are studying the genome of the indigenous inhabitants of Siberia.